Insulin Resistance: The Metabolic Syndrome X, Vol. 12
Author: Gerald M Reaven
In Insulin Resistance: The Metabolic Syndrome X, outstanding investigators thoughtfully summarize our current understanding of how insulin resistance and its compensating hyperinsulinemia (Syndrome X) play a major role in the pathogenesis and clinical course of high blood pressure and cardiovascular disease - the so-called diseases of Western civilization - as well as polycystic ovary disease. Under the aegis of Gerald Reaven, the discoverer of Syndrome X, the distinguished authorities writing here detail for the first time the pathophysiological consequences and the clinical syndromes, excluding Type 2 diabetes, related to insulin resistance. They also examine the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Each author has been encouraged to present a point of view that reflects their unique insights.
New England Journal of Medicine
This book is an excellent and useful compendium of information about this rapidly moving field. It will be an essential addition to the libraries of those interested in any of the disorders linked to this prevalent metabolic state.
David A. Ehrmann
This volume in the Contemporary Endocrinology Series is a multiauthored text designed to summarize the current understanding of the importance of insulin resistance, particularly as it relates to non-diabetic states. The purpose is to provide the reader with information about the importance of insulin resistance in non-diabetic states. It is appropriate for any clinician or investigator who encounters adult patients. The spectrum of metabolic disturbances associated with insulin resistance is broad, making this book appealing to generalists as well as subspecialists. This book is structured in three parts. Part one covers genetic and environmental factors affecting insulin action; part two covers the pathophysiology of insulin resistance; and part three deals with clinical syndromes associated with insulin resistance. This book is particularly useful in that it bridges the gaps in what is known about the fundamental elements of insulin action and the clinical sequelae. For example, the complexities of the relationship between obesity and insulin resistance are clearly handled. This is an excellent and welcome addition to the field: concise, clearly written, and current.
Doody Review Services
Reviewer: David A. Ehrmann, MD (University of Chicago Medical Center)
Description: This volume in the Contemporary Endocrinology Series is a multiauthored text designed to summarize the current understanding of the importance of insulin resistance, particularly as it relates to non-diabetic states.
Purpose: The purpose is to provide the reader with information about the importance of insulin resistance in non-diabetic states.
Audience: It is appropriate for any clinician or investigator who encounters adult patients. The spectrum of metabolic disturbances associated with insulin resistance is broad, making this book appealing to generalists as well as subspecialists.
Features: This book is structured in three parts. Part one covers genetic and environmental factors affecting insulin action; part two covers the pathophysiology of insulin resistance; and part three deals with clinical syndromes associated with insulin resistance. This book is particularly useful in that it bridges the gaps in what is known about the fundamental elements of insulin action and the clinical sequelae. For example, the complexities of the relationship between obesity and insulin resistance are clearly handled.
Assessment: This is an excellent and welcome addition to the field: concise, clearly written, and current.
Booknews
Reaven, who discovered Syndrome X, assembles summaries of the current understanding of how insulin resistance and its compensating hyperinsulinemia play a major role in the pathogenesis and clinical course of high blood pressure, cardiovascular disease, and polycystic ovary syndrome. They detail the pathophysiological consequences and the clinical syndromes besides Type 2 diabetes that are related to insulin resistance, and explore the genetic and lifestyle factors that contribute to the wide differences in insulin action that exist in the population at large. Of interest to both researchers and clinicians. Annotation c. by Book News, Inc., Portland, Or.
Rating
3 Stars from Doody
Table of Contents:
| Preface | ||
| Contributors | ||
| Pt. I | Genetic and Environmental Factors Affecting Insulin Action | |
| 1 | Genetics of Insulin Resistance | 3 |
| 2 | Ethnic Variation in Insulin Resistance and Risk of Type 2 Diabetes | 19 |
| 3 | Fetal Effects on Insulin Resistance and Glucose Tolerance | 35 |
| 4 | Obesity and Insulin Resistance: Epidemiologic, Metabolic, and Molecular Aspects | 51 |
| 5 | The Role of Body Fat Distribution in Insulin Resistance | 83 |
| 6 | Physical Activity and Insulin Resistance in Man | 97 |
| 7 | Insulin Resistance in Smokers and Other Long-Term Users of Nicotine | 121 |
| Pt. II | Pathophysiology of Insulin Resistance | |
| 8 | Insulin Resistance and Inhibitors of Insulin Receptor Tyrosine Kinase | 139 |
| 9 | NMR Studies on the Mechanism of Insulin Resistance | 159 |
| 10 | Skeletal Muscle Insulin Resistance in Humans: Cellular Mechanisms | 179 |
| 11 | The Role of the Liver in Insulin Action and Resistance | 197 |
| 12 | The Pathophysiological Consequences of Adipose Tissue Insulin Resistance | 233 |
| 13 | Insulin Action and Endothelial Function | 247 |
| Pt. III | Clinical Syndromes Associated with Insulin Resistance | |
| 14 | Insulin Resistance and Dyslipidemia: Implications for Coronary Heart Disease Risk | 267 |
| 15 | Insulin Resistance and Blood Pressure | 281 |
| 16 | Microalbuminuria and Insulin Resistance | 309 |
| 17 | PAI-I, Obesity, and Insulin Resistance | 317 |
| 18 | Insulin Resistance and Cardiovascular Disease | 333 |
| 19 | Insulin Resistance Effects on Sex Hormones and Ovulation in the Polycystic Ovary Syndrome | 347 |
| Index | 367 |
Interesting textbook: Adventures in Social Research or Crystal Reports 85
Exercise for Older Adults: Ace's Guide for Fitness Professionals
Author: American Council on Exercis
Exercise for Older Adults: ACE's Guide for Fitness Professionals offers the essential information fitness professionals need to provide older adults with safe and effective fitness programming, from the physiology of aging to the techniques and tools for motivating and communicating with older adults. Personal trainers, activity directors, health educators and fitness facility managers are among those who will benefit from this valuable resource.
Palaestra
...A complete overview of basic principles...to meet older adults' special fitness needs....contains many helpful tables and is introduced with an overview of tis contents....An extensive glossary adds to the value of this excellent publication.
Booknews
Covers professional trainer how-tos. Chapters discuss physiological and functional changes associated with aging, ways to effectively communicate with older adults, the adaptation of exercise programs to age-related medical conditions, the physiological and psychological effects of common medications, assessment protocols, a variety of useful exercises with guidelines and ideas for necessary modifications, and suggestions on how to design and structure programs for individuals and groups.
Palaestra
...[A] complete overview of basic principles...to meet older adults' special fitness needs....contains many helpful tables [and] is introduced with an overview of tis contents....An extensive glossary adds to the value of this excellent publication.
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